effect of saffron extract and crocin in serum metabolites

Saffron against Components of Metabolic Syndrome: Current

IP Rat Saffron methanolic extract crocin and safranal significantly reduced the fasting blood glucose and HbA1c levels but significantly increased the blood insulin levels (2) Crocin (2) 50 and 150 mg/kg (3) Safranal (3) 0 25 and 0 5 mL/kg Arasteh et al 26 Insulin resist- demia None Saffron extract 50 mg/kg IP Rat Hydromethanolic extract of

Neuroprotective Activities of Saffron and Crocin

Sep 21 2016The effect of saffron and crocin on improving ethanol-induced impairment of learning behaviors of mice in passive avoidance tasks has been clear Further we did make clear that saffron and crocin prevent the inhibitory effect of ethanol on long-term potentiation (LTP) in the dentate gyrus

Beneficial effects of saffron (Crocus sativus L ) in

This neuroprotective effect of the saffron extract could be due to its anti-inflammatory effects and its antioxidant capacity (Fernndez-Albarral et al 2019) The only studies on using saffron in patients with glaucoma are focused on analyzing its possible ocular hypotensive effect and have obtained contradictory results

High

ABSTRACT Purpose Exercise training and some herbal components have an anticancer function and can suppress tumor growth However the role of these protective factors in altering breast cancer–related gene expression is still unknown Thus this study aimed to assess the effect of 4 wk of high-intensity interval training (HIIT) and saffron (Crocus sativus L ) aqueous extract (SAE) on Sirtuin

The effect of hydroalcoholic Saffron (Crocus sativus L

Fatin Najwa Ramli Azliana Abu Bakar Sajak Faridah Abas Zulfitri Azuan Mat Daud Azrina Azlan Effect of Saffron Extract and Crocin in Serum Metabolites of Induced Obesity Rats BioMed Research International 10 1155/2020/1247946 2020 (1-15) (2020)

Pharmacological properties of Crocus Sativus Linn (Saffron)

Saffron extract or its active constituents crocetin and crocin may be useful for the treatment for neurodegenerative disorders accompanying memory impairment Crocin was also showed to prevent the death of neurons provoked by internal and external apoptotic stimuli by suppressing the TNF α induced cell death P Effects on blood pressure:

4 Proven Benefits of Saffron for Arthritis How to Use it

The effects of different doses of saffron on neuropathic pain induced by chronic injury were observed Hyperalgesia (increased pain) was also measured if any There was a notable decrease in hyperalgesia after administration of saffron and crocin (30 mg/kg) At low doses crocin was ineffective

Neuroprotective Activities of Saffron and Crocin

Sep 21 2016The effect of saffron and crocin on improving ethanol-induced impairment of learning behaviors of mice in passive avoidance tasks has been clear Further we did make clear that saffron and crocin prevent the inhibitory effect of ethanol on long-term potentiation (LTP) in the dentate gyrus

Protective effects of saffron extract and crocin

Oct 22 2016Saffron is the dried stigma of Crocus sativus L flower which commonly used as a natural remedy to enhance health and even fights disease in the Middle-East and Southeast Asian countries This study was aimed to investigate protective effect of saffron extract and crocin in fatty liver tissue of high-fat diet induced obese rats A total of 36 healthy male Sprague Dawley rats were divided

Protective Effect of Crocus sativus Stigma Extract and

This study was designed to examine the effect of aqueous extract of Crocus sativus stigmas (CSE) and crocin (trans-crocin 4) on methyl methanesulfonate (MMS)–induced DNA damage in multiple mice organs using the comet assay Adult male NMRI mice in different groups were treated with either physiological saline (10 mL/Kg intraperitoneal [ip]) CSE (80 mg/Kg ip) crocin (400 mg/Kg ip) MMS

Crocetin and Crocin from Saffron in Cancer Chemotherapy

Natural substances derived from plants such as polyphenols flavonoids carotenoids alkaloids and others can be biologically active and have a wide spectrum of effects The protective effects of Saffron carotenoids (crocin and crocetin) have been extensively studied mainly for their antioxidant properties however they have various other

Saffron: A potential candidate for a novel anticancer drug

Fatin Najwa Ramli Azliana Abu Bakar Sajak Faridah Abas Zulfitri Azuan Mat Daud Azrina Azlan Effect of Saffron Extract and Crocin in Serum Metabolites of Induced Obesity Rats BioMed Research International 10 1155/2020/1247946 2020 (1-15) (2020)

Saffron: A potential candidate for a novel anticancer drug

Fatin Najwa Ramli Azliana Abu Bakar Sajak Faridah Abas Zulfitri Azuan Mat Daud Azrina Azlan Effect of Saffron Extract and Crocin in Serum Metabolites of Induced Obesity Rats BioMed Research International 10 1155/2020/1247946 2020 (1-15) (2020)

Effect of Aqueous Extract of Crocus sativus L (Saffron

Effect of aqueous extract of Crocus sativus L (saffron) stigma on serum levels of gonadotropins and folliculogenesis in adult rats J Appl Anim Res 35: 49-52 To examine the effects of aqueous extract of Crocus sativus L (saffron) stigma on serum levels of follicle

Influence of Different Extraction Methods and the Storage

coloring strength The degradation of saffron pigments seemed to be fast so this step of analysis should be short In the recent IS0 3632-2-2010 the extraction period was severely reduced to one hour of magnetic stirring that may influenced the concentration of the secondary metabolites of saffron 350 300 250 E1% Crocin at 440nm 100 E1

Nutrients

Saffron is a natural compound that has been used for centuries in many parts of the world as a food colorant and additive It was shown to have the ability to mitigate various disorders through its known anti-inflammatory and anti-oxidant properties Several studies have shown the effectiveness of saffron in the treatment of various chronic diseases like inflammatory bowel diseases Alzheimer

Effect of Saffron Extract and Crocin in Serum Metabolites

Research Article Effect of Saffron Extract and Crocin in Serum Metabolites of Induced Obesity Rats Fatin Najwa Ramli 1 Azliana Abu Bakar Sajak 1 Faridah Abas 2 3 Zulfitri Azuan Mat Daud 1 and Azrina Azlan 1 4 5 1Department of Nutrition and Dietetics Faculty of Medicine and Health Sciences Universiti Putra Malaysia 43400 UPM Serdang Selangor Malaysia

Nutrients

Saffron is a natural compound that has been used for centuries in many parts of the world as a food colorant and additive It was shown to have the ability to mitigate various disorders through its known anti-inflammatory and anti-oxidant properties Several studies have shown the effectiveness of saffron in the treatment of various chronic diseases like inflammatory bowel diseases Alzheimer

Pharmacological properties of Crocus Sativus Linn (Saffron)

Saffron extract or its active constituents crocetin and crocin may be useful for the treatment for neurodegenerative disorders accompanying memory impairment Crocin was also showed to prevent the death of neurons provoked by internal and external apoptotic stimuli by suppressing the TNF α induced cell death P Effects on blood pressure:

Anticarcinogenic effect of saffron (Crocus sativus L ) and

In another study ROS did not play effective role in the cytotoxic effect of saffron extract on HeLa cell lines in which apoptosis or programmed cell death plays an important role The effect of crocin and its nano liposomal was examined on HeLa cells by measuring apoptotic cell via flow cytometry method Results indicated that crocin and its

Avicenna Journal of Phytomedicine

Review Article Crocus sativus Saffron Crocin Smooth muscle Relaxant effect Despite a few studies demonstrating some immunomodulatory effects for saffron extract SAF as a major constituent of saffron did not induce any marked effects in immune system parameters of mice

Effects of saffron extract and its constituent crocin on

This effect of saffron extract is attributed to crocin (crocetin di‐gentiobiose ester) but not crocetin Saffron extract or its active constituents crocetin and crocin could be useful as a treatment for neurodegenerative disorders accompanying memory impairment

A 1H

The metabolic profile of serum in obese rat after the administration of saffron extract (80mg/ kg) and crocin (80mg/kg) were deviated from negative control This results indicated that administration of saffron extract (80mg/ kg) and crocin (80mg/kg) could effectively improve disturbed metabolism in obese rats induced by HFD

Nutrients

Saffron (Crocus sativus L ) and its main constituents i e crocin and crocetin are natural carotenoid compounds which have been reported to possess a wide spectrum of properties and induce pleiotropic anti-inflammatory anti-oxidative and neuroprotective effects An increasing number of experimental animal and human studies have investigated the effects and mechanistic pathways of these

Metabolic effects of Crocus sativus and protective action

In our study we approached the potent effect of saffron on glucose metabolism in two dimensions Diabetes per se and NAFLD as a collateral manifestation In the former case Crocus sativus effect on tissue sensitivity to insulin is well-documented Our results are in accordance with the existing literature data (11 15 23) The decrease in